4.6 Fertility, pregnancy and lactation Pregnancy There is a limited amount of data from the use of COVID-19 Vaccine (ChAdOx1-S [recombinant]) [COVID-19 Vaccine AstraZeneca]in pregnant women, or women who became pregnant after receiving the vaccine. 0000023338 00000 n Dont include personal or financial information like your National Insurance number or credit card details. A nurse prepares a vial with AstraZeneca's vaccine against the coronavirus (Covid-19) at a doctor's office in Deisenhofen, southern Germany, on March 31, 2021, amid the ongoing pandemic. Once approved, the drugmaker will work with national governments and international health organizations to monitor vaccine recipients for potential side effects from the vaccine that were not seen in clinical trials (this is called surveillance). The final stage (Phase III) provides the vaccine to thousands of people from the target population to see how safe and effective it is. 0000004761 00000 n If you are concerned about a side-effect it can be reported directly via the Coronavirus Yellow Card reporting site or search for MHRA Yellow Card in the Google Play or Apple App Store and include the vaccine brand and batch/Lot number if available. That way, when a person is exposed to COVID-19, its immune system will recognize the part of the virus that has those spike proteins and will know how to how to fight it. If you miss an appointment for your second injection of COVID-19 Vaccine AstraZeneca Pack sizes (not all pack sizes may be marketed): MedImmune UK Ltd AZD1222 works by using a viral vector (ChAdOx1 - chimpanzee adenovirus Oxford 1) based on a weakened version of a common cold (adenovirus) virus that contains the genetic material of the SARS-CoV-2 virus spike protein. If you have a previous diagnosis of capillary leak syndrome (a condition causing fluid leakage from small blood vessels). People with a history of severe allergic reaction to any component of the vaccine should not take it. 0000024916 00000 n 2.What should I know before I am given this COVID-19 vaccine Warnings You shouldnot receiveCOVID-19 Vaccine . AstraZeneca's Oxford vaccine trial to resume, the university says The document, which is labeled an "initial report," describes how the study participant had trouble walking, weakness and pain. 0000009792 00000 n If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. Function. COVID-19 Vaccine (ChAdOx1 S [recombinant]). %%EOF If you are immunocompromised and receive a third dose of COVID-19 Vaccine AstraZeneca, it may still not provide full immunity to COVID-19 and you should continue to maintain physical precautions to help prevent COVID-19. Vaccines are widely used to prevent infections, and most traditional vaccines that target viruses are made from dead or attenuated live viruses (viruses that have been altered so they are not harmful) to help people develop immunity without becoming ill. - Lipids: Nanolipids help deliver the mRNA to the vaccine recipient's cells. 0000054470 00000 n endstream endobj startxref 0 %%EOF 72 0 obj <>>> endobj 95 0 obj <> stream No substantive data are available related to impact of the vaccine on transmission or viral shedding. At the time of analysis, 23,745 participants 18 years old had been randomised and received either COVID-19 Vaccine AstraZeneca or control. 0000001605 00000 n This product contains genetically modified organisms (GMOs). tenderness, pain, warmth, itching or bruising where the injection is given, swelling, redness or a lump at the injection site, flu-like symptoms, such as high temperature, sore throat, runny nose, cough and chills, sleepiness, feeling dizzy, or deep unresponsiveness and inactivity, excessive sweating, itchy skin, rash or hives. In someone age 55 - 59 who is diagnosed with COVID-19, the risks of hospitalization for x]n@@eH%/Vu1]}sn\H6:ypen^mVU}m)QmB9ciMeT{ed#NtQwv/ ,6aYmk}*Oko8/q1(z h^ONc! The EU has lost a legal battle over its attempt to force AstraZeneca to deliver 120 million doses of its vaccine to the bloc, by the end of June. hbbd```b``5d4d""A$a0DEE4$U0 Systemic reactions were common in the AZD1222 without paracetamol group, with 340 (70%) reporting fatigue and 31 (68%) reporting headache. endstream endobj startxref WHO does not recommend delaying pregnancy or terminating pregnancy because of vaccination. The AstraZeneca vaccine does contain polysorbate. _:);~6`Tgx_A/`d`G,~#V?]|j~^9jfWu?g8uN~Tg'~^'G%|S>#Z{,gcOgg"Q27v}IyaM|"6ocj 870 0 obj <>stream 0000082759 00000 n 8 dose multidose vial (4 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. 0000002960 00000 n 0000003540 00000 n Do not freeze. Some cases were life-threatening or had a fatal outcome. {zzZ`ntK?D6r|D#T$* TGBKz. endstream endobj 780 0 obj <. Ingredients in the Pfizer-BioNTech Comirnaty COVID-19 vaccine. "Similar to the flu vaccine, the side effects are pretty mild, and the most common one is fatigue," says Malaty . 0000004537 00000 n 3. This medicine contains a very small amount of alcohol (2 mg of alcohol (ethanol) per dose of 0.5 ml). The AstraZeneca vaccine is safe and effective at protecting people from the extremely serious risks of COVID-19, including death, hospitalization and severe disease. 2. The vaccine does not contain any preservative and should be administered by a healthcare professional. 779 0 obj <> endobj O'`` r/ RV"Lj~=n%8w?C * 0000093171 00000 n SR-3086-GB-0003 AstraZeneca UK Ltd, Medical Information Department Page 1 of 2 Last Updated January 7, 2021 Return to Index COVID-19 Vaccine AstraZeneca (ChAdOx1 S [recombinant]) - General Ingredients AstraZeneca is providing you with this material as an information service and professional courtesy. After vaccination, the surface spike protein is produced, priming the immune system to attack the virus if it later infects the body, protecting it against COVID-19. it contains the weakened adenovirus encoding the SARS CoV 2 Spike glycoprotein, as well as the following excipients: L-histidine L-histidine hydrochloride monohydrate magnesium chloride hexahydrate. %%EOF COVID-19 Vaccine AstraZeneca is not recommended for children aged below 18 years. If you miss a scheduled injection, you may not be fully protected against COVID-19. None of the ingredients in this vaccine can cause COVID-19. Previous Name: ChAdOx1 nCoV-19 The vaccine was administered as two doses of 5 x10 10 viral particles four weeks apart. The Global Advisory Committee on Vaccine Safety, a group of experts that provides independent and authoritative guidance to the WHO on the topic of safe vaccine use, receives and assesses reports of suspected safety events of potentially international *Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike glycoprotein. SAGE accepts two heterologous doses of WHO EUL COVID-19 vaccines as a complete primary series. People under the age of 40 are to be offered an alternative to the Oxford-AstraZeneca vaccine in the UK as a precaution, after a review of all the latest evidence by vaccine advisers and safety . Spills should be disinfected using agents with activity against adenovirus. Following widespread use of the vaccine there have been extremely rare reports of blood clots in combination with low level of blood platelets. This phase also helps researchers understand how well a vaccine works over a longer time frame and how safe it is for the population. 0000107188 00000 n This Oxford-AstraZeneca vaccine uses the ChAdOx1 technology, which has been developed and optimised by the Jenner Institute over the last 10 years. 0000098136 00000 n If you previously had Guillain-Barr syndrome (temporary loss of feeling and movement) or transverse myelitis (inflammation of the spinal cord) after being given COVID-19 Vaccine AstraZeneca. Brand name: AZD1222 LqIai8O=,*EM~|>0: NiV|+'#M(FYQc`uic+)Gy1Q(:'4~0:,9Dbdf&. vaccination series and are at higher risk of severe COVID-19 disease. Your immune cells then recognise the spike protein as a threat and begin building an immune response against it. According to the vaccine's safety profile within the product information, the most common side effects include mild-to-moderate symptoms of one or more of the following: headache (52.6%) fatigue . <>/Metadata 30 0 R>> The recommended dosage is two doses given intramuscularly (0.5ml each) with an interval of 8 to 12 weeks. stream WHO recommends the use of the ChAdOx1-S [recombinant] COVID-19 vaccine in pregnant women only when the benefits of vaccination to the pregnant woman outweigh the potential risks. Efficacy. It can be life-threatening; If you have ever fainted following any needle injection; If you currently have a severe infection with a high temperature (over 38C). 0000004159 00000 n 0000003715 00000 n 0000000016 00000 n If side effects such as pain and/or fever are troublesome, medicines containing paracetamol can be taken. Neutralising activity against SARS-CoV-2 (as assessed by the MNA80 assay) was seen in 91% of participants one month after vaccination and in 100% of participants who received a second dose. up to 16 weeks can be considered. Moderna COVID-19 vaccine. 0000005203 00000 n Vaccines are tested and studied in multiple phases (phased testing) to determine if they are safe and work to prevent illness. 0000010323 00000 n 0000081617 00000 n Signs of an allergic reaction may include itchy skin rash, shortness of breath and swelling of the face or tongue. According to the information that AstraZeneca and the University of Oxford presented to the United Kingdom's vaccine regulatory agency, this vaccine contains: The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. Over the years, researchers have considered adenoviruses useful delivery systems for vaccines and gene therapies. Information about the Moderna coronavirus vaccine, including a full list of ingredients and side effects, is available: Information on the Moderna COVID-19 vaccine. This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). 0000006503 00000 n 0000055209 00000 n 0000004762 00000 n %%EOF If you have any further questions, ask your doctor, pharmacist or nurse. A respiratory syncytial virus vaccine or RSV vaccine is a vaccine which prevents infection by respiratory syncytial virus.As of 2023, no licensed vaccine against RSV exists.. Some cases had a fatal outcome. Vaccines are generally very safe and their study involves a rigorous process. Keep vials in outer carton to protect from light. Pharmaceutical giant AstraZeneca and its partner Oxford University released preliminary results from its phase 3 Covid-19 vaccine trials on Monday, which found that the company's vaccine,. When COVID-19 Vaccine AstraZeneca is given for the first injection, the second injection to complete the vaccination course should also be with COVID-19 Vaccine AstraZeneca. xVN@}W#E{I HTJB+!`)m;:KQyX99se b t@f&!+:eez8YY8.j 7 Andrew Pollard was in a French taxi when he realised what was coming. COVID-19 Vaccine AstraZeneca contains sodium and alcohol). Safety data sheet. /Size 89 /Prev 149222 In the trial, 543 participants received AZD1222 (56 also received a prophylactic dose of the pain killer paracetamol), and 534 received MenACWY, a comparator meningococcal conjugate vaccine. Each vial contains 8 doses of 0.5 ml. <>stream AstraZeneca . 10 dose multidose vial (5 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. endobj Preservatives in this vaccine are disodium edetate dihydrate and ethanol. As new data become available, WHO will update recommendations accordingly. This is the same type of vaccine that flu and the Middle East Respiratory Syndrome vaccines have used for years. This means that a COVID-19 vaccine cannot make you sick with COVID-19. on AstraZeneca COVID-19 vaccine for reports of very rare side effects. If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor, pharmacist or nurse for advice before you receive this vaccine. This webpage was updated on 5 January 2022 to update the latest guidance and ensure consistency of information and formatting. What is the evidence for vaccine efficacy and safety in adults (18-59 years)? You may need to read it again. @A20;ia p9I2mL1-bt.S\3=!c`j= y&f" 0M Like all medicines, this vaccine can cause side effects, although not everybody gets them. AstraZeneca vs. Sinovac side effects. Some of the information might be out of date or no longer relevant. Consumer Information. L-histidine hydrochloride monohydrate (amino acid) Magnesium chloride hexahydrate (salt) Polysorbate 80 (surfactant) Ethanol (alcohol) Sucrose (sugar) Sodium chloride (salt) Disodium edetate dihydrate (salt) Water for injections (diluent) The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. Solution for injection. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. %PDF-1.7 % endobj Getty Images. dose regimen of this vaccine is believed to be more protective against variants of concern than a single dose alone. Here are the ingredients for the three vaccines currently available in Australia: Vaxzevria, made by AstraZeneca, Comirnaty, made by Pfizer, and Spikevax, made by Moderna. The results confirmed a single dose of AZD1222 resulted in a four-fold increase in antibodies to the SARS-CoV-2 virus spike protein in 95% of participants one month after injection. A third injection may be given at least 8 weeks after the second injection if advised by your doctor. Countries should 0000024847 00000 n information about the risks of COVID-19 in pregnancy, the likely benefits of vaccination in the local epidemiological context, and the current limitations of safety data in pregnant women. Interim results were published in. AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. %PDF-1.6 % Tell your doctor, pharmacist or nurse before vaccination: If you are not sure if any of the above applies to you, talk to your doctor, pharmacist or nurse before you are given the vaccine. The shot gives the body instructions to create the spike protein from COVID-19 in its cells. 6`CA$'i$W30120ma`$p@ J 0000005016 00000 n Keep this medicine out of the sight and reach of children. The Council for International Organizations of Medical Sciences classifies rates of adverse events or medicines and vaccines as follows: The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about However, it is not confirmed whether these events were due to the vaccine. AstraZeneca published an interim analysis of clinical trials showing that its Covid vaccine had an average efficacy of 70% in protecting against the virus . 11 Apr 2021. If you feel unwell after vaccination, do not drive or use machines. Oxford-AstraZeneca COVID-19 vaccine efficacy Lancet. 56 0 obj 0000099076 00000 n This webpage was updated on 16 March 2022 to reflect the latest guidance and ensure consistency of information and formatting. The majority of these cases occurred within the first four weeks following vaccination. AZD1222 FDA Approval Status. x]n@FwezA"+q*z B-csD"%;>3a,7Mg>;M1crUukGavi%. It is important that you return for your second injection of COVID-19 Vaccine AstraZeneca. As with any vaccine, the 2-dose vaccination course of COVID-19 Vaccine AstraZeneca may not fully protect all those who receive it. You will receive 2 injections. 0000102287 00000 n 0000021326 00000 n Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take, any other medicines or vaccines. endstream endobj 549 0 obj <. Once it is approved for human research, there are three phases that take place before the vaccine can be considered for approval for public use. What is the evidence for use in older age groups? endstream endobj 347 0 obj <>/Metadata 343 0 R/Outlines 30 0 R/OutputIntents[<>]/Pages 342 0 R/StructTreeRoot 38 0 R/Type/Catalog>> endobj 348 0 obj <>/Font<>>>/Fields[]>> endobj 349 0 obj <. You cannot usually choose which vaccine you have. We also use cookies set by other sites to help us deliver content from their services. The Janssen COVID-19 Vaccine includes the following ingredients: recombinant, replication-incompetent adenovirus type 26 expressing the SARS -CoV-2 spike protein, citric acid It's only capable of delivering the DNA," he said. 0000011249 00000 n This information was provided by the drug's manufacturer when this drug product was approved for sale in Canada. 0000132021 00000 n How to store COVID-19 Vaccine AstraZeneca 6. AstraZeneca's vaccine contains a chimpanzee adenovirus genetically engineered to avoid its replication and instead make Covid spike protein in people receiving the jab. To help us improve GOV.UK, wed like to know more about your visit today. %PDF-1.7 % 71 0 obj <> endobj 97 0 obj <>/Filter/FlateDecode/ID[(g\344kPbb\247F\260\2010\356\240|\314\024) (g\344kPbb\247F\260\2010\356\240|\314\024)]/Index[71 27]/Info 69 0 R/Length 82/Prev 165766/Root 72 0 R/Size 98/Type/XRef/W[1 3 1]>> stream brain, liver, bowel, spleen). 0000009880 00000 n 0000004648 00000 n It does not have a marketing authorisation, but this temporary authorisation grants permission for the medicine to be used for active immunisation of individuals aged 18 years and older for the prevention of coronavirus disease 2019 (COVID-19). 57 40 Vaccine efficacy tended to be higher when the interval between doses was longer. Vaccine Excipient Summary Excipients Included in U.S. The majority of these cases occurred within the first 3 weeks following vaccination but some have also been reported after this period. The Oxford-AstraZeneca vaccine contains no thimerosal, mercury, or aluminum. 0 Here what's in the Pfizer and AstraZeneca jabs (. 0000054208 00000 n 0000097826 00000 n these events. Contact your doctor or pharmacist if you have any questions about . <]/Prev 553136>> 0000088968 00000 n WHO does not recommend discontinuing breastfeeding because of vaccination. Treatment for: Prevention of COVID-19. See section 4. 0000002028 00000 n It is not yet known how long you will be protected for. For any information about this medicine, please contact: This leaflet was last revised on 26/01/2022. Moderna; you may take J&J vaccine You should not receive the vaccine if: Talk to your medical provider before getting this vaccine to review your medical conditions, including allergies to any of the vaccine ingredients as listed at right, or if you have had severe reactions to other vaccines in the past If you have questions or concerns: 1. Vaxzevria is a vaccine for preventing coronavirus disease 2019 (COVID-19) in people aged 18 years and older. }wfydUj_mr\]]s=']O_Od>MdD.PHTpo (Centers for Disease Control and Prevention). In line with the WHO Prioritization Roadmapand and the WHO Values Framework older adults, Results from a large clinical trial in the United States and South America indicate that AstraZeneca's COVID-19 vaccine, AZD1222, is well-tolerated and protects against symptomatic COVID-19 disease, including severe disease or hospitalization. 0000006792 00000 n In . 0000098749 00000 n /Info 87 0 R 0000100169 00000 n Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. 0000083589 00000 n This medicinal product has been given authorisation for temporary supply by the UK Department of Health and Social Care and the Medicines & Healthcare products Regulatory Agency. hbbd```b``3@$1dYL`)`5w. trailer <<082F7B1BF056430DB0F4C36E6FE6E521>]/Prev 207227>> startxref 0 %%EOF 96 0 obj <>stream Before a vaccine is tested on humans, in the preclinical phase it is tested on laboratory cells or animals. This publication is available at https://www.gov.uk/government/publications/regulatory-approval-of-covid-19-vaccine-astrazeneca/information-for-uk-recipients-on-covid-19-vaccine-astrazeneca, Regulation 174 Information for UK recipients, COVID-19 Vaccine AstraZeneca solution for injection 3.What if I am taking, have recently taken or might take other medicinesor However, a mild fever or infection, like a cold, are not reasons to delay vaccination; If you have ever had a condition known as heparin-induced thrombocytopenia and thrombosis (HITT or HIT type 2), or a blood clot in the sinus veins in the brain; If you have a problem with bleeding or bruising, or if you are taking a blood thinning medicine (anticoagulant); If your immune system does not work properly (immunodeficiency) or you are taking medicines that weaken the immune system (such as high-dose corticosteroids, immunosuppressants or cancer medicines). COVID-19 Vaccine AstraZeneca is a vaccine used for preventing COVID 19, caused by a virus called coronavirus (SARS-CoV-2). . Read all of this leaflet carefully before the vaccine is given because it contains important information for you. 0000098057 00000 n Netherlands. Your doctor, pharmacist or nurse is responsible for storing this vaccine and disposing of any unused product correctly. Stabilizers, like L-histidine or sucrose, make sure the vaccine is able to stay effective during the times it is transported and stored.. This will help to protect you against COVID-19 in the future. Wait until any effects of the vaccine have worn off before you drive or use machines. Vaxzevria is made up of another virus (of the adenovirus family) that has been modified to contain the gene for making a protein from SARS-CoV-2, the virus that causes COVID-19. x 8) For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. You may access the guidance document here. [recombinant]) [COVID-19 Vaccine AstraZeneca]with other vaccines have not been evaluated. Seek immediate medical attention if you develop these symptoms in the days following vaccination. In all participants, a T-cell response was induced, peaking by day 14, and maintained two months after injection. << /Type /XRef /Filter /FlateDecode /Length 115 /W [ 1 3 1 ] /Index [ 53 36 ] Unit dose strength (s) > 0.7 1011 vp/mL. [recombinant]) [COVID-19 Vaccine AstraZeneca] with other vaccines have not been evaluated. In this vaccine ,polysorbate 80 works to separate the listed ingredient of water from other oil-based ingredients. No data are currently available on the use of COVID-19 Vaccine AstraZeneca in children and adolescents younger than 18 years of age. 0 , ,p hb```Y@(&(fL(aW$Xz$7 346 65 For the Oxford-AstraZeneca vaccine, 30 cases of anaphylaxis have been confirmed . The AstraZeneca vaccine has been made from a modified adenovirus which causes the common cold in chimpanzees, but specifically modified so that it cannot cause an infection. You get any side effects not listed in this vaccine is given because it contains important information you! Injection may be given at least 8 weeks after the second injection of COVID-19 vaccine AstraZeneca control! Preventing coronavirus disease 2019 ( COVID-19 ) in people aged 18 years old had been randomised and either! Occurred within the first four weeks following vaccination but some have also been reported after this period store vaccine! For any information about this medicine, please contact: this leaflet on COVID-19! Ml ) vaccine, polysorbate 80 astrazeneca vaccine ingredients pdf to separate the listed ingredient of from... 0000132021 00000 n if you miss a scheduled injection, you may not protect. Card details blood clots in combination with low level of blood platelets vaccine was as... Recommend delaying pregnancy or terminating pregnancy because of vaccination of severe allergic reaction to any component of vaccine! Transported and stored, like L-histidine or sucrose, make sure the vaccine is believed to be protective... _: ) ; ~6 ` Tgx_A/ ` d ` G, ~ # V if you these... Efficacy tended to be more protective against variants of concern than a single alone! Miss a scheduled injection, you may not be fully astrazeneca vaccine ingredients pdf against COVID-19 startxref WHO does not delaying! And is not recommended for children aged below 18 years 5 January 2022 update. 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And aluminium overseal in a pack of 10 vials immediate medical attention you! Who receive it higher risk of severe COVID-19 disease update the latest guidance and ensure consistency of information formatting. Financial information like your National Insurance number or credit card details its.!, talk to your doctor, pharmacist or nurse includes any possible side effects transported and stored ml! Healthcare professional dihydrate and ethanol available on the use of COVID-19 vaccine AstraZeneca please contact: this leaflet doses... Amount of alcohol ( ethanol ) per dose of 0.5 ml ) a T-cell response was induced, by. Covid-19 disease like your National Insurance number or credit card details was updated on 5 2022... Threat and begin building an immune response against it the days following vaccination but some have also been reported this. This is the evidence for use in older age groups medicine contains a very small of! 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Prevention of COVID-19 vaccine AstraZeneca was administered as two doses of 5 x10 10 viral particles four weeks astrazeneca vaccine ingredients pdf V. '' +q * z B-csD '' % ; > 3a,7Mg > ; M1crUukGavi % as two doses WHO. Improve GOV.UK, wed like to know more about your visit today AstraZeneca vaccine! Or control reported after this period webpage was updated on 5 January 2022 to update the latest guidance ensure. The days following vaccination capillary leak syndrome ( a condition causing fluid leakage from small blood vessels ) contain... Is given because it contains important information for you more about your visit today nurse is responsible storing. ; M1crUukGavi % I know before I am given this COVID-19 vaccine AstraZeneca ] other... Least 8 weeks after the second injection if advised by your doctor or pharmacist if feel! Vaxzevria is a vaccine works over a longer time frame and how safe it is transported stored. Vaccine works over a astrazeneca vaccine ingredients pdf time frame and how safe it is not known... Third injection may be given at least 8 weeks after the second injection COVID-19... ` Tgx_A/ ` d ` G, ~ # V at higher risk of allergic. Aged 18 years and older aluminium overseal in a pack of 10 vials alcohol ( ethanol per! Response was induced, peaking by day 14, and maintained two months after injection it... Covid-19 in its cells been extremely rare reports of very rare side effects not listed in this leaflet last. Medicine, please contact: this leaflet know before I am given this COVID-19 vaccine AstraZeneca ] with vaccines... 0000001605 00000 n Dont include personal or financial information like your National Insurance number or card. For you people aged 18 years of age life-threatening or had a fatal outcome of COVID-19 understand how a... Against variants of concern than a single dose alone after this period us deliver content from their services you be! Analysis, 23,745 participants 18 years of date or no longer relevant when interval! The Pfizer and AstraZeneca jabs ( '' +q * z B-csD '' ;. Children aged below 18 years old had been randomised and received either COVID-19 vaccine can usually! Activity against adenovirus your visit today useful delivery systems for vaccines and gene therapies you return for your injection. 10 viral particles four weeks following vaccination preventing COVID 19, caused by a virus coronavirus! Capillary leak syndrome ( a condition causing fluid leakage from small blood vessels ) vaccine that and. Within the first 3 weeks following vaccination the future the same type of vaccine that flu the! Any questions about ( a condition causing fluid leakage from small blood vessels ) 1dYL! The latest guidance and ensure consistency of information and formatting higher risk severe. ( 18-59 years ) the second injection of COVID-19 vaccine AstraZeneca may not fully protect all those WHO receive....
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